Scenario 1
Two Managers are in an MDR pair, and you are adding the Sensor configuration information in Manager 1.
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If connection A between Manager 1 and Manager 2 is over IPv4 network, and you are adding Sensor configuration in Manager 1, the communication between Manager 1 and Sensor (that is, connection B) should also be over IPv4 network.
Similarly, if connection A between Manager 1 and Manager 2 is over IPv6 network, and you are adding Sensor configuration in Manager 1, the communication between Manager 1 and Sensor (that is, connection B) should also be over IPv6 network.
If connection A between Manager 1 and Manager 2 is over both IPv4 and IPv6 networks, and you are adding Sensor configuration in Manager 1, the communication between Manager 1 and Sensor (that is, connection B) can be configured over either IPv4 or IPv6 network.
Scenario 2
Suppose Manager 1 is standalone (not part of an MDR pair), and you want to add a peer Manager (that is, Manager 2) with Manager 1 to form an MDR pair.
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If the communication between Sensors and Manager 1 (that is, connection B and C) is over IPv4 network, the communication between Manager 1 and Manager 2 (that is, connection A) should also be configured for IPv4 network.
Similarly, if the communication between Sensors and Manager 1 (that is, connection B and C) is over IPv6 network, the communication between Manager 1 and Manager 2 (that is, connection A) should also be configured for IPv6 network.
If B and C support both IPv4 and IPv6 networks, A can be configured to support either IPv4 or IPv6 network.